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KMID : 1149520180020030123
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Cardiovasclar Imaging Asia
2018 Volume.2 No. 3 p.123 ~ p.128
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Determining Whether Tube Voltages and Contrast Flow Rates have an Impact on a Test Bolus-Based Contrast-Enhancement-Prediction Algorithm during Coronary CT Angiography
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Zhu Xiaomei
Yu Yusheng
Tang Lijun
Zhang Hong
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Abstract
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Objective: To assess whether tube voltages and contrast flow rates have an impact on a test bolus (TB)-based contrast-enhancement-prediction (CEP) algorithm during coronary computed tomographic angiography (CCTA).
Materials and Methods: A total of 188 anonymized CCTA examinations following TB scans were collected. During TB, a tube voltage of 100 kV and contrast flow rate of 3.5 mL/s were applied for Group 1 and 120 kV and 4.5 mL/s for Group 2. True aortic enhancements were extracted with a region of interest at the ascending aorta (AAo). TB signals and group information were used as independent variables in a stepwise linear regression analysis to predict aortic enhancement. For each patient, the errors in predicted aortic enhancements were calculated.
Results: Time to peak enhancement in the AAo (PTAAo) and peak enhancement in the descending aorta (PEDAo) during the TB study had significant correlations with AAo (AAo=?125.627+1.619×PEDAo+16.236×PTAAo r=0.782, p<0.001). The CEP algorithm without group information presented a minor systemic underestimation in Group 1 [?8 Hounsfield unit (HU)] and an overestimation in Group 2 (8 HU).
Conclusion: The TB-based CEP of aortic enhancement is feasible. The tube voltages and contrast flow rates during TB scanning were statistically significant, but resulted in a clinical negligible impact on the CEP algorithm.
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KEYWORD
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Tube voltage, Contrast agent, Coronary, Computed tomography angiography, Contrast enhancement prediction
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